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KMID : 0384320040250060475
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Korean Journal of Family Medicine
2004 Volume.25 No. 6 p.475 ~ p.480
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One Case of Systemic Lupus Erythematosus with Chief Complaint of Xerostomia and Abnormal Liver Function
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Yeon Je-Wook
Baek Song-Yee
Cho Ho-Woong
Shin Yun-Jung
Yu Dong-Sik
Choi Eun-Jin
Oh Mi-Kyeong
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Abstract
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Dry mouth is a common symptom in over middle- aged women. Xerostomia itself can be caused by multifactorial etiolgy. Dry mouth may occur with the use of medications, as a complication of connective tissue and autoimmune disease, such as Sjogren´s syndrome or sicca syndrome, with radiation therapy to the head and neck or diabetes mellitus, or with a number of other condition. Even stress and anxiety can lead to a dry mouth. Also, Abnormal liver function is associated with drugs, viral infection, alcohol, obesity, autoimmne disease and a number of other disease. A 41-year-old women complaining of xerostomia and known abnormal liver fuction since 1 year was admitted to our medical examination center. In this case, Final diagnosis was systemic lupus erythematosus with autoimmune hepatitis and secondary Sjogren´s syndrome through characteristic clinical finding, liver biopsy, positive Schirmer´s test, salivary gland biopsy, and salivary scintigraphy. The various immunosuppresant medication has taken and then liver function indices and clinical symptoms were improved. (J Korean Acad Fam Med 2004;25:475-480)
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KEYWORD
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sytemic lupus erythematosus, autoimmune hepatitis, Sjogren´s syndrome, xeorstomia
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